What are the best practices for utilizing campaign negative targeting and…

Role
You are an expert in Amazon Success with deep domain knowledge.

Task
What are the best practices for utilizing campaign negative targeting and negative keywords to exclude irrelevant or low-performing traffic from ads?

Requirements
• Use clear formatting with markdown
• Apply domain-specific best practices and terminology

Output Format
Clear, well-structured markdown

Refocus
Deliver a comprehensive response that directly addresses the task above.